Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 185
interventional 168
Observational 15
Registry 2

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 34
Other 30
Device 27
Drug|placebo 17
Procedure 13
Behavioral 11
Dietary Supplement 5
Dietary Supplement|placebo 5
Other|placebo 5
Behavioral|Device 3
Drug|Other 3
Device|Drug 2
Device|Other 2
Device|placebo 2
Dietary Supplement|Drug 2
Drug|Other|placebo 2
Drug|Procedure 2
Combination Product 1
Device|Procedure 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 54
NA 23
Canada 11
Brazil 9
Germany 8
India 7
Italy 6
China 4
Iran, Islamic Republic of 4
Turkey 4
Israel 3
Sweden 3
United Kingdom 3
Colombia 2
Denmark 2
Malaysia 2
Portugal 2
Thailand 2
Austria|Germany 1
Dominican Republic 1
Egypt 1
France 1
Greece 1
Guatemala 1
Iraq 1
Japan 1
Jordan 1
Kuwait 1
Norway 1
Pakistan 1
Puerto Rico 1
Saudi Arabia 1
South Africa 1
Spain 1
Syrian Arab Republic 1
Taiwan 1
United States|Guatemala 1

Sites per Study

Site_count Study_Count
1 156
2 8
3 3
4 1

Phase

Phase Study_Count
N/A 103
Phase 4 25
Phase 2 15
Phase 3 15
Phase 1/Phase 2 5
Phase 1 3
Early Phase 1 2

Number of Arms

Number_of_Arms Count_of_Studies
1 3
2 103
3 41
4 14
5 1
10 1
NA 5

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.3 Phase.4
Min. 35 2.0000 54.00000 30.0 14.00000 32.0 20.00
1st Qu. 39 35.0000 72.00000 45.0 34.50000 39.0 59.00
Median 43 70.0000 90.00000 50.0 60.00000 66.0 84.00
Mean 43 98.8932 87.33333 70.8 83.33333 86.4 110.76
3rd Qu. 47 111.0000 104.00000 94.0 93.50000 107.0 135.00
Max. 51 746.0000 118.00000 135.0 319.00000 300.0 324.00

Trial Group Type

group_type Group_Count
Experimental 164
Active Comparator 123
Placebo Comparator 71
No Intervention 23
Other 15
Sham Comparator 7
NA 5

Intervention Model

intervention_model Study_Count
Parallel Assignment 131
Crossover Assignment 21
Single Group Assignment 10
Factorial Assignment 5
Sequential Assignment 1

Primary Purpose

primary_purpose Study_Count
Treatment 85
Prevention 56
Supportive Care 7
Basic Science 6
Other 4
NA 4
Diagnostic 2
Health Services Research 2
Screening 2

Observational Studies

Studies by Country

Country Study_Count
United States 5
NA 4
Turkey 2
China 1
Greece 1
Italy 1
United Kingdom 1

Sites per Study

Site_count Study_Count
1 15

Enrollment Metrics

Measure Observational
Min 35.0000
1st Qu 83.0000
Median 100.0000
Mean 538.3333
3rd Qu 300.0000
Max 2890.0000

Observation Model

observational_model Study_Count
Other 6
Cohort 3
Case-Only 2
Case Control 2
Case-Control 1
NA 1

Time Perspective

time_perspective Study_Count
Cross-Sectional 5
Prospective 5
Retrospective 5

Registries

Studies by Country

Country Study_Count
Turkey 1
United States 1

Sites per Study

Site_count Study_Count
1 2

Enrollment Metrics

Measure Registries
Min 40.00
1st Qu 51.75
Median 63.50
Mean 63.50
3rd Qu 75.25
Max 87.00

Registry Model

observational_model Study_Count
Case-Only 1
Other 1

Time Perspective

time_perspective Study_Count
Cross-Sectional 1
Prospective 1

Follow-up

target_duration Study_Count
1 Day 1
1 Month 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT04455269 The Efficacy of Full Mouth Erythritol Powder Air-Polishing Therapy (FM-EPAPT) Versus Traditional Ultrasonic Debridment (UD): a Randomized Controlled Study. https://ClinicalTrials.gov/show/NCT04455269 Completed Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 2019-04-01
NCT03378401 Study to Assess the Inhibition of Plaque Formation in Subjects With a Gingival Index ≤1.5 https://ClinicalTrials.gov/show/NCT03378401 Completed Schülke & Mayr GmbH 2018-09-14
NCT03336957 Stress and Gingival Inflammation in Non-pregnant and Pregnant Women https://ClinicalTrials.gov/show/NCT03336957 Completed Tokat Gaziosmanpasa University 2017-01-01
NCT03329105 Efficacy of a Rinse Containing Sea Salt and Lysozyme on Biofilm and Gingival Health https://ClinicalTrials.gov/show/NCT03329105 Completed University of Saskatchewan 2017-08-24
NCT03251001 Acellular Dermal Matrix Allograft Versus Free Gingival Graft https://ClinicalTrials.gov/show/NCT03251001 Completed University of Sao Paulo 2017-11-30
NCT03237624 Functional Chewing Gum in Reduction of Gingival Inflammation https://ClinicalTrials.gov/show/NCT03237624 Completed University of Maryland, Baltimore 2020-01-31
NCT03219840 Cetylpyridium Chloride (CPC) Based Chewing Gum and Gingivitis https://ClinicalTrials.gov/show/NCT03219840 Completed The University of Texas Health Science Center, Houston 2018-09-08
NCT03214406 Clinical Evaluation of the Efficacy of a Marketed Dentifrice on Plaque and Gingivitis https://ClinicalTrials.gov/show/NCT03214406 Completed Church & Dwight Company, Inc. 2010-08-03
NCT03196648 Randomized Trial of a Gum Health Formulation https://ClinicalTrials.gov/show/NCT03196648 Completed Glo Science, Inc. 2016-11-30
NCT03158350 Toothbrush Wear and Its Effect on Subgingival Inflammation Using Two Different Brushing Techniques https://ClinicalTrials.gov/show/NCT03158350 Completed Tufts University 2016-01-31
NCT03154021 Next Science Antimicrobial Mouth Rinse Study https://ClinicalTrials.gov/show/NCT03154021 Completed University of Florida 2018-03-08
NCT03120559 Improving Dental Floss Adherence and Gingival Health With SMS and an Innovative Floss Holder https://ClinicalTrials.gov/show/NCT03120559 Completed University of Lisbon 2016-03-30
NCT03117153 Effect of a Liquid Toothpaste on Periodontal Disease https://ClinicalTrials.gov/show/NCT03117153 Completed Dong-A Pharmaceutical 2014-09-15
NCT03047798 The Effect of Mouthrinses Containing Bamboo Salt, Magnolia Bark and Centella Asiatica on Reducing Plaque and Gingivitis https://ClinicalTrials.gov/show/NCT03047798 Completed Seoul National University 2014-09-30
NCT03047759 Comparison of Two Interdental Cleaners https://ClinicalTrials.gov/show/NCT03047759 Completed All Sum Research Center Ltd. 2016-08-31
NCT03030820 Oral Gut Liver Axis in Cirrhosis https://ClinicalTrials.gov/show/NCT03030820 Completed Virginia Commonwealth University 2018-03-31
NCT02980497 Antiplaque/Antigingivitis Efficacy of Essential Oil Mouthrinses in Six-Month Study https://ClinicalTrials.gov/show/NCT02980497 Completed Johnson & Johnson Consumer and Personal Products Worldwide 2014-03-31
NCT02937636 To Investigate the Gingivitis Efficacy of a Stannous Fluoride Dentifrice in a Chinese Population https://ClinicalTrials.gov/show/NCT02937636 Completed GlaxoSmithKline 2017-12-22
NCT02949583 Mouthwash of Pomegranate Against Biofilm and Gingival Inflammation in School Children https://ClinicalTrials.gov/show/NCT02949583 Completed Universidade Estadual da Paraiba 2012-05-31
NCT02940821 Assessing the Effects of Three Oral Care Regimens https://ClinicalTrials.gov/show/NCT02940821 Completed Pearl Network 2017-07-27
NCT02906982 Evaluating the Efficacy of a Gum Health Formulation on Teeth Whitening in Patients With Gingivitis and Periodontitis https://ClinicalTrials.gov/show/NCT02906982 Completed Glo Science, Inc. 2015-12-31
NCT02906098 Intervention Study of Oral Health Education Programs Directed to Adolescents https://ClinicalTrials.gov/show/NCT02906098 Completed Göteborg University 2020-03-31
NCT02894593 Alcohol-free Essential Oils Containing Mouthrinse Efficacy on 3-day Supragingival Plaque Regrowth https://ClinicalTrials.gov/show/NCT02894593 Completed University of L’Aquila 2015-10-31
NCT02884817 Essential Oil+ELA, Plaque and Gingivitis https://ClinicalTrials.gov/show/NCT02884817 Completed University of Oslo 2015-10-31
NCT02861937 Estimation of Interleukin-21 Levels in Gingival Crevicular Fluid in Patients With Periodontal Health and Disease Following Non-surgical Periodontal Therapy: A Clinico-biochemical Study https://ClinicalTrials.gov/show/NCT02861937 Completed Krishnadevaraya College of Dental Sciences & Hospital 2014-09-30
NCT02836223 Evaluation of the Addition of an Interdental Cleaning Device to Manual Brushing on Gingival Health https://ClinicalTrials.gov/show/NCT02836223 Completed Water Pik, Inc. 2016-08-31
NCT02775019 Health Impact of L.Reuteri Consumption in Crew Members of a Naval Ship at Sea https://ClinicalTrials.gov/show/NCT02775019 Completed Wuerzburg University Hospital 2016-08-31
NCT02750943 Potential of Stannous Fluoride Toothpaste to Reduce Gum Disease https://ClinicalTrials.gov/show/NCT02750943 Completed GlaxoSmithKline 2016-03-01
NCT02725983 Intra-oral Camera in Gingival Health https://ClinicalTrials.gov/show/NCT02725983 Completed University of Lisbon 2015-02-28
NCT02709785 SmartMouth Advanced Clinical Formula Clinical Research Design Protocol https://ClinicalTrials.gov/show/NCT02709785 Completed St. Louis University 2017-05-31
NCT02699931 Efficacy of Electric 3D Versus Manual Toothbrushes in Patients With Fixed Orthodontic Appliances https://ClinicalTrials.gov/show/NCT02699931 Completed National and Kapodistrian University of Athens 2019-04-30
NCT02669979 Domiciliary Professional Oral Care for Dependent Elderly https://ClinicalTrials.gov/show/NCT02669979 Completed Karolinska Institutet 2017-04-30
NCT02668809 Oral Hygiene Intervention Pilot Study https://ClinicalTrials.gov/show/NCT02668809 Completed University of Iowa 2018-06-30
NCT02648139 A Randomized, Controlled, Double-blind Clinical Trial of Surinam Cherry Dentifrice With Anti-gingivitis Properties https://ClinicalTrials.gov/show/NCT02648139 Completed Federal University of Paraíba 2010-02-28
NCT02639377 Efficacy of 0.12% Chlorhexidine Gluconate for Peri-implant Mucositis and Gingivitis https://ClinicalTrials.gov/show/NCT02639377 Completed Universidade Federal do Rio Grande do Norte 2013-12-31
NCT02616042 The Effect of New Dentifrices Containing Centella Asiatica and Bamboo Salt on Reducing Plaque and Gingivitis https://ClinicalTrials.gov/show/NCT02616042 Completed LG Household & Health Care Ltd. 2009-07-31
NCT02597192 Clinical Effects of Bacillus Containing Oral Hygiene Products on Gingivitis: a Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT02597192 Completed Cukurova University 2014-12-31
NCT02574221 A Pilot Study to Evaluate a Molecular Method for Plaque https://ClinicalTrials.gov/show/NCT02574221 Completed Procter and Gamble 2015-10-31
NCT01799226 Study of the Anti-Inflammatory Effects of Colgate Total® During an Experimental Gingivitis Model https://ClinicalTrials.gov/show/NCT01799226 Completed University of Michigan 2013-12-31
NCT02552589 Effect of Toothpaste on the Reduction of Plaque and Inflammation https://ClinicalTrials.gov/show/NCT02552589 Completed Technische Universität Dresden 2016-02-29
NCT02546206 Probiotic Yoghurt Effect on Experimental Gingivitis https://ClinicalTrials.gov/show/NCT02546206 Completed Marmara University 2012-05-31
NCT02543060 A Pilot Study to Evaluate a Method for Plaque When Comparing Stannous Fluoride Toothpaste to a Regular Dentifrice https://ClinicalTrials.gov/show/NCT02543060 Completed Procter and Gamble 2015-08-31
NCT02545244 Effectiveness of Black Tea Mouthwash on Plaque Formation https://ClinicalTrials.gov/show/NCT02545244 Completed Sri Hasanamba Dental College and Hospital 2015-06-30
NCT02521155 “Safeguard Your Smile” an Oral Health Literacy Intervention Promoting Positive Oral Hygiene Self-care Behavior https://ClinicalTrials.gov/show/NCT02521155 Completed Université de Montréal 2015-10-31
NCT02515929 Prospective Double-Blind Randomized Controlled Clinical Trial in the Gingivitis Prevention With OPCs https://ClinicalTrials.gov/show/NCT02515929 Completed University of Seville 2013-12-31
NCT02419144 Good Oral Health - A Bi-level Intervention to Improve Older Adult Oral Health https://ClinicalTrials.gov/show/NCT02419144 Active, not recruiting UConn Health 2020-06-30
NCT02412358 Clinical Comparision of Three Types of Toothbrushes Pulsar, Crossaction and Butler on Gingivitis and Plaque Removal https://ClinicalTrials.gov/show/NCT02412358 Completed Mashhad University of Medical Sciences 2008-11-30
NCT02401360 A Study to Assess Clinical Gingivitis and Microbiome Following the Use of Multiple Oral Hygiene Products https://ClinicalTrials.gov/show/NCT02401360 Completed Procter and Gamble 2013-04-30
NCT02366689 Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash) https://ClinicalTrials.gov/show/NCT02366689 Completed Colgate Palmolive 2014-12-31
NCT02360995 The Clinical Investigation of Toothpaste as Compared to Toothpaste and Mouthwash in Reducing Plaque and Gingivitis: A Six-week Clinical Study in the US https://ClinicalTrials.gov/show/NCT02360995 Completed Colgate Palmolive 2014-08-31
NCT02027597 Improving Oral Health With Serious Games https://ClinicalTrials.gov/show/NCT02027597 Completed University of Washington 2010-12-31
NCT02320162 School-based Oral Health Education Program Using Experiential Learning https://ClinicalTrials.gov/show/NCT02320162 Completed Marquette University 2012-06-30
NCT02313558 Efficacy of a Commercial Dentifrice Containing Ilex Rotunda Thunb Extract for Dental Plaque and Gingivitis https://ClinicalTrials.gov/show/NCT02313558 Completed Sun Yat-sen University 2014-11-30
NCT02243046 The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and Gingivitis https://ClinicalTrials.gov/show/NCT02243046 Completed Colgate Palmolive 2015-05-31
NCT02235532 Effects of Aloe Vera Toothpaste on Periodontal Parameters https://ClinicalTrials.gov/show/NCT02235532 Completed Islamic Azad University, Tehran 2014-02-28
NCT02233998 A Clinical Trial to Test the Effect of Marketed Mouth Rinses on Decreasing Plaque and Gum Inflammation https://ClinicalTrials.gov/show/NCT02233998 Completed Johnson & Johnson Consumer and Personal Products Worldwide 2014-09-30
NCT02227485 Iranian Traditional Mouth Rinse Punica Granatum Pleniflora (Golnaar) in Treatment of Gingivitis in Diabetic Patients https://ClinicalTrials.gov/show/NCT02227485 Completed Shiraz University of Medical Sciences 2014-11-30
NCT02215473 Bacteremia in Periodontal Patients https://ClinicalTrials.gov/show/NCT02215473 Completed University of Taubate 2013-12-31
NCT02203812 Effect of Probiotic Lozenge on Gingivitis and Periodontitis https://ClinicalTrials.gov/show/NCT02203812 Completed CD Pharma India Pvt. Ltd. 2016-02-29
NCT02193165 The Clinical Efficacy of Three Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste and a Mouthwash in Controlling Dental Plaque and Gingivitis https://ClinicalTrials.gov/show/NCT02193165 Completed Colgate Palmolive 2014-08-31
NCT02187016 Efficacy and Safety Study of Interproximal Cleaning Modalities on Oral Health https://ClinicalTrials.gov/show/NCT02187016 Completed Philips Oral Healthcare 2014-07-31
NCT02168335 The Efficacy of OrasaltsTM in the Treatment of Gingivitis https://ClinicalTrials.gov/show/NCT02168335 Completed University of Johannesburg 2014-09-30
NCT02160418 Incentives for Daily Tooth Brushing to Reduce Gingivitis https://ClinicalTrials.gov/show/NCT02160418 Completed University of Pennsylvania 2017-04-14
NCT02154594 "The Efficacy of Acacia Catechu Mouthrinse as Antiplaque and Antigingivitis Agent in Fixed Orthodontic Appliance Patients. https://ClinicalTrials.gov/show/NCT02154594 Completed Tatyasaheb Kore Dental College 2014-03-31
NCT02123563 Mechanical-chemical Gingival Therapy in Diabetics and/or Obese https://ClinicalTrials.gov/show/NCT02123563 Completed University of Taubate 2013-06-30
NCT02080273 Six Month Plaque and Gingivitis Study Using Colgate Total Toothpaste https://ClinicalTrials.gov/show/NCT02080273 Completed Colgate Palmolive 2013-11-30
NCT02071199 Treatment of Human Gingivitis With Amnion-derived Cellular Cytokine Solution (ACCS) https://ClinicalTrials.gov/show/NCT02071199 Completed Noveome Biotherapeutics, formerly Stemnion 2015-10-31
NCT02065414 A Clinical Trial to Test the Effect of Experimental Mouth Rinse on Gum Disease https://ClinicalTrials.gov/show/NCT02065414 Completed Johnson & Johnson Consumer and Personal Products Worldwide 2014-06-30
NCT01317446 Effect of Mouthrinsing on Inflammation of the Gums. https://ClinicalTrials.gov/show/NCT01317446 Completed Technische Universität Dresden 2012-01-31
NCT01307358 A Study Comparing the Interproximal Plaque and Gingivitis Effects of Three Interdental Cleaning Modalities https://ClinicalTrials.gov/show/NCT01307358 Completed University of North Carolina, Chapel Hill 2011-04-30
NCT01271231 Study on Periodontal Treatment in Diabetic Patients https://ClinicalTrials.gov/show/NCT01271231 Completed Universidad de Antioquia 2012-07-31
NCT01976806 The Effects of DHA on Periodontitis https://ClinicalTrials.gov/show/NCT01976806 Completed Beth Israel Deaconess Medical Center 2011-09-30
NCT01954849 Assessment of a Probiotic to Treat Gingivitis in Pediatric Patients https://ClinicalTrials.gov/show/NCT01954849 Completed Lawson Health Research Institute 2014-12-31
NCT01941797 Experimental Peri-implant Mucositis in Humans https://ClinicalTrials.gov/show/NCT01941797 Completed UConn Health 2014-09-30
NCT01902095 Clinical Effects of Tooth Powder on Gingivitis https://ClinicalTrials.gov/show/NCT01902095 Completed Sheikh Zayed Federal Postgraduate Medical Institute 2011-07-31
NCT01898000 “Triphala” - A New Herbal Mouthwash in Gingivitis https://ClinicalTrials.gov/show/NCT01898000 Completed Government Dental College and Research Institute, Bangalore 2013-04-30
NCT01877421 Safety and Tolerability of Antiplaque Chewing Gum in a Gingivitis Population https://ClinicalTrials.gov/show/NCT01877421 Completed U.S. Army Medical Research and Development Command 2015-08-25
NCT01811316 A Clinical Trial to Evaluate Long-term Efficacy and Safety of Lozenges Containing Lactobacilli Reuteri (Prodentisâ„¢) on Gingivitis https://ClinicalTrials.gov/show/NCT01811316 Completed Sunstar Americas 2015-01-31
NCT01751178 An Efficacy Study of Chlorhexidine Mouthwashes https://ClinicalTrials.gov/show/NCT01751178 Completed GlaxoSmithKline 2013-03-31
NCT01630837 Frequency of Oral Hygiene https://ClinicalTrials.gov/show/NCT01630837 Completed Universidade Federal de Santa Maria 2012-02-29
NCT01601145 Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study https://ClinicalTrials.gov/show/NCT01601145 Completed Università degli Studi di Sassari 2012-07-31
NCT01593540 Clinical Examination of Metal Free Interdental Brushes https://ClinicalTrials.gov/show/NCT01593540 Completed University of Freiburg 2011-08-31
NCT01578603 Effects of Two Sugar Substituted Chewing Gums on Caries and Gingivitis Variables https://ClinicalTrials.gov/show/NCT01578603 Completed Universidad de Antioquia 2012-05-31
NCT01559987 Dental Plaque Removal Study https://ClinicalTrials.gov/show/NCT01559987 Completed University of North Carolina, Chapel Hill 2012-05-31
NCT01549587 Oral Hygiene and Maternity Outcomes Multicenter Study (OHMOM) https://ClinicalTrials.gov/show/NCT01549587 Completed Procter and Gamble 2014-02-28
NCT01419626 A Study to Determine the Effects of Adding an Experimental Device With Mouthrinse to Oral Care Regimen https://ClinicalTrials.gov/show/NCT01419626 Completed Johnson & Johnson Consumer and Personal Products Worldwide 2011-08-31
NCT01411618 Efficacy of Essential Oil Mouthwash With and Without Alcohol: a 3-Day Plaque Accumulation Model https://ClinicalTrials.gov/show/NCT01411618 Completed University of L’Aquila 2010-09-30
NCT01388023 Day Long Prevention of Oral Malodor With a Palatal Patch (SmellX) Containing A Herbal Formula https://ClinicalTrials.gov/show/NCT01388023 Completed Hadassah Medical Organization 2012-11-30
NCT01336179 Comparative Effect of Chewing Sticks and Toothbrushing on Plaque Removal and Gingival Health https://ClinicalTrials.gov/show/NCT01336179 Completed Taibah University 2011-04-30
NCT00554034 Effect of Herbal Extracts on Gingival Inflammation https://ClinicalTrials.gov/show/NCT00554034 Completed Shaare Zedek Medical Center 2009-03-31
NCT04390997 Determination of the Levels of Lipocalin-2 and Semaphorin3A https://ClinicalTrials.gov/show/NCT04390997 Recruiting Izmir Katip Celebi University 2020-09-30
NCT00471783 Flossing With Chlorhexidine https://ClinicalTrials.gov/show/NCT00471783 Completed University of British Columbia 2006-12-31
NCT04328753 The Effect of SOW Mouthwash on the Level of IL_1β in GCF and Some Clinical Periodontal Parameters for Patients With Gingivitis https://ClinicalTrials.gov/show/NCT04328753 Recruiting University of Baghdad 2020-05-20
NCT04317768 Effect of Oral Health Education on Oral Health Status, Treatment Needs and Barriers to Care https://ClinicalTrials.gov/show/NCT04317768 Active, not recruiting Jordan University of Science and Technology 2020-07-31
NCT04315532 The Effect of Periodontal Treatment on Stress and Pregnancy Relationship https://ClinicalTrials.gov/show/NCT04315532 Completed Tokat Gaziosmanpasa University 2016-10-31
NCT04251858 Evaluation of Oral Condition and the Effect of Dental Treatment on Physical Parameters of Athletes https://ClinicalTrials.gov/show/NCT04251858 Recruiting Universidade Metropolitana de Santos 2020-11-10
NCT04221334 Clinical Investigation Examining Plaque and Gingivitis Connected Toothbrush Compared to Non-Connected Toothbrush https://ClinicalTrials.gov/show/NCT04221334 Completed Colgate Palmolive 2019-07-03
NCT04218994 The Effect of Instructed Dental Flossing on Interdental Gingival Bleeding: A Randomized Controlled Clinical Trial https://ClinicalTrials.gov/show/NCT04218994 Completed Tufts University 2018-12-02
NCT04198610 Evaluation and Correlation of Serum Fetuin-A Levels in Periodontal Health and Disease: A Clinico-biochemical Study https://ClinicalTrials.gov/show/NCT04198610 Completed Krishnadevaraya College of Dental Sciences & Hospital 2017-08-28
NCT04190485 To Evaluate the Efficacy of Probiotics Toothpastes in Improvement of Gingivitis and Prevention of Periodontal Diseases Via Modulating the Oral Microbiota https://ClinicalTrials.gov/show/NCT04190485 Recruiting GenMont Biotech Incorporation 2021-05-14
NCT04140643 Ozone Therapy for the Home Oral Hygiene of the Pregnant Woman. https://ClinicalTrials.gov/show/NCT04140643 Recruiting IRCCS San Raffaele 2019-11-30
NCT04123665 A Phase 3 Clinical Study Investigating the Gingivitis Efficacy of a Test Dentifrice Containing Stannous Fluoride https://ClinicalTrials.gov/show/NCT04123665 Completed GlaxoSmithKline 2013-12-11
NCT04105569 Atlas of Experimental Gingivitis in Humans https://ClinicalTrials.gov/show/NCT04105569 Active, not recruiting University of North Carolina, Chapel Hill 2020-06-01
NCT04092075 Safety and Efficacy of the ToothWave -12 Weeks Calculus Study https://ClinicalTrials.gov/show/NCT04092075 Recruiting Home Skinovations Ltd. 2020-04-30
NCT04071210 Impact of Oral Probiotics on Oral Homeostasis https://ClinicalTrials.gov/show/NCT04071210 Recruiting University of Copenhagen 2020-03-01
NCT04057430 Effectiveness of the GumChucks® Flossing System Compared to String Floss for Interdental Plaque Removal in Children https://ClinicalTrials.gov/show/NCT04057430 Completed University of California, Los Angeles 2017-02-26
NCT04050722 A Clinical Study Investigating the Efficacy of a Stannous Fluoride Dentifrice in Improving Gingival Health After Twice Daily Use for 3 Weeks https://ClinicalTrials.gov/show/NCT04050722 Completed GlaxoSmithKline 2019-11-13
NCT04033575 Clinical Investigation of a Toothpaste Containing Stannous Fluoride as Compared to Colgate Fluoride Toothpaste https://ClinicalTrials.gov/show/NCT04033575 Completed Colgate Palmolive 2019-06-06
NCT04032548 Effectiveness of Propolis Mouthwash on Gingivitis https://ClinicalTrials.gov/show/NCT04032548 Completed Mahsa University 2019-03-11
NCT04023097 Self-selection Study of the Toothwave Toothbrush https://ClinicalTrials.gov/show/NCT04023097 Completed Home Skinovations Ltd. 2019-07-09
NCT04015427 Cement Excess at Single Implant Crowns Malmö/Lund https://ClinicalTrials.gov/show/NCT04015427 Recruiting University of Zurich 2019-12-31
NCT04003298 Efficacy of the Addition of a Power Interdental Device to an Electric Toothbrush on Gingival Health. https://ClinicalTrials.gov/show/NCT04003298 Completed Water Pik, Inc. 2019-07-26
NCT03989427 The Effectiveness of Brushing and Flossing Sequence on Control of Plaque and Gingival Inflammation https://ClinicalTrials.gov/show/NCT03989427 Completed Melaka Manipal Medical College 2019-12-15
NCT03962777 Efficacy of Oil Pulling Therapy on Supragingival Plaque Growth https://ClinicalTrials.gov/show/NCT03962777 Completed Baskent University 2019-05-09
NCT03936556 A Clinical Study to Assess the Effects of a Stannous Fluoride Dentifrice on Plaque and Gingivitis https://ClinicalTrials.gov/show/NCT03936556 Completed Procter and Gamble 2018-06-03
NCT03885323 ToothWave Plaque and Gingivitis Study https://ClinicalTrials.gov/show/NCT03885323 Completed Home Skinovations Ltd. 2019-04-15
NCT03863093 Evaluation of Air Polishing With Ultrasonic Debridement in the Treatment of Initial Periodontal Pockets https://ClinicalTrials.gov/show/NCT03863093 Completed Syrian Private University 2019-09-30
NCT03852056 The Clinical Investigation of a New Toothpaste Containing Stannous Fluoride as Compared to a Commercially Available Fluoride Toothpaste in Reducing Plaque and Gingivitis https://ClinicalTrials.gov/show/NCT03852056 Completed Colgate Palmolive 2017-12-07
NCT03841825 Effects of Active Reminders and Motivational Techniques on Oral Hygiene and Gingival Health in Orthodontic Patients https://ClinicalTrials.gov/show/NCT03841825 Active, not recruiting Virginia Commonwealth University 2020-08-31
NCT03839719 OSE as a Pre-procedural Mouth Rinse: A Clinical and Microbiological Study. https://ClinicalTrials.gov/show/NCT03839719 Completed Government College of Dentistry, Indore 2019-04-26
NCT03765125 Dietary Collagen Peptides and Periodontal Inflammation https://ClinicalTrials.gov/show/NCT03765125 Recruiting Wuerzburg University Hospital 2019-08-31
NCT03750955 Induced Gingivitis & Intra-oral Imaging https://ClinicalTrials.gov/show/NCT03750955 Completed University of Washington 2019-06-03
NCT03713567 Clinical, Immunological and Microbiological Evaluation of Experimental Gingivitis and Peri-implant Mucositis https://ClinicalTrials.gov/show/NCT03713567 Completed University of Campinas, Brazil 2018-03-20
NCT03700840 Interdental Microbiota Among Adolescents https://ClinicalTrials.gov/show/NCT03700840 Recruiting Université Montpellier 2018-12-31
NCT03694444 A Study of the C3 Complement Inhibitor AMY-101 in Adults With Gingivitis https://ClinicalTrials.gov/show/NCT03694444 Recruiting Amyndas Pharmaceuticals S.A. 2020-09-30
NCT03641989 Correlation Between Oral Health and Systemic Inflammation (COHESION) https://ClinicalTrials.gov/show/NCT03641989 Completed Marshfield Clinic Research Foundation 2019-12-30
NCT03640065 Evaluation of The Effect of Live Probiotic Cultures Present in Fermented Dairy Product (Yogurt) Versus The Effect of Freeze-Dried Probiotic Sachets on Gingival Bleeding of Adolescents https://ClinicalTrials.gov/show/NCT03640065 Recruiting Cairo University 2020-03-31
NCT03624647 A Clinical Comparison of an Experimental Power Brush Compared to a Manual Toothbrush https://ClinicalTrials.gov/show/NCT03624647 Completed Procter and Gamble 2018-09-14
NCT03550651 Evaluation of Antiplaque Efficacy of Licorice Extract Mouthrinse & HSS and Their Comparison With EO & CHX Mouthrinse https://ClinicalTrials.gov/show/NCT03550651 Completed Government College of Dentistry, Indore 2017-05-15
NCT03522571 Experimental Gingivitis in Patients With Altered Passive Eruption https://ClinicalTrials.gov/show/NCT03522571 Completed University of Roma La Sapienza 2017-07-19
NCT03508999 Effectiveness of Metronidazole Gel and Mobile SMS Reminders on Gingivitis in Orthodontic Patients https://ClinicalTrials.gov/show/NCT03508999 Completed Aga Khan University 2018-11-30
NCT03474146 Comparative Evaluation of Antiplaque and Antigingivitis Efficacy of Ocimum Sanctum (Tulsi) Extract https://ClinicalTrials.gov/show/NCT03474146 Completed Government College of Dentistry, Indore 2017-07-22
NCT03471325 A Comparison of the Outcomes of Two Existing Routine Clinical Therapies for Dental Prophylaxis https://ClinicalTrials.gov/show/NCT03471325 Completed National University Health System, Singapore 2017-09-30
NCT03455192 Synbiotic as an Adjunct to Mechanical Treatment of Gingivitis https://ClinicalTrials.gov/show/NCT03455192 Completed Kırıkkale University 2015-06-29
NCT03445286 Silver Diamine Fluoride and Gingivitis in Geriatric Patients https://ClinicalTrials.gov/show/NCT03445286 Recruiting Texas A & M University Baylor College Of Dentistry 2020-05-31
NCT03439969 A 8-month Study on the Use of Intra-oral Camera and Text Messages on Gingivitis Control https://ClinicalTrials.gov/show/NCT03439969 Completed University of Lisbon 2015-02-28
NCT03416985 A Comparative Study of Electric Toothbrushes for the Efficacy Plaque Removal and the Effect on Plaque Accumulation and Gingivitis. https://ClinicalTrials.gov/show/NCT03416985 Completed University of California, Los Angeles 2018-11-01
NCT01236963 Essential Oils Mouthrinse and Dental Floss, Comparison of Efficacy on Interproximal Gingivitis and Dental Plaque Accumulation https://ClinicalTrials.gov/show/NCT01236963 Completed University of Lisbon 2008-01-31
NCT01236950 Study of an Essential Oil and a Delmopinol Mouthrinse Effect on Dental Plaque Accumulation Index, Gingivitis Index and on Streptococcus Mutans, Lactobacillus, Aerobic and Anaerobic Oral Bacteria Colony Counts. https://ClinicalTrials.gov/show/NCT01236950 Completed University of Lisbon 2008-04-30
NCT01224158 Study of an Experimental Toothbrush for Treatment and Prevention of Gingivitis https://ClinicalTrials.gov/show/NCT01224158 Completed Johnson & Johnson Consumer and Personal Products Worldwide 2010-10-29
NCT01154257 Comparison of Swabs and Toothbrushes in Cleaning the Teeth of Mechanically Ventilated Patients https://ClinicalTrials.gov/show/NCT01154257 Completed Cardiff and Vale University Health Board 2011-06-30
NCT01142843 Preliminary Evidence of the Efficacy of a Mouthwash Containing 5% Propolis for the Control of Plaque and Gingivitis https://ClinicalTrials.gov/show/NCT01142843 Completed Federal University of Minas Gerais 2009-10-31
NCT01103102 Dose-Response Study of Iocide Oral Rinse https://ClinicalTrials.gov/show/NCT01103102 Completed Biomedical Development Corporation 2012-01-31
NCT00972803 The Effects of Pistacia Mutica on De Novo Dental Plaque Formation, Gingival Inflammation and Oral Microorganisms https://ClinicalTrials.gov/show/NCT00972803 Completed Tabriz University NA
NCT00964860 A Controlled Clinical Study to Determine the Gingivitis Benefit of Flossing https://ClinicalTrials.gov/show/NCT00964860 Completed Procter and Gamble 2009-08-31
NCT00941668 Evaluate Inflammation Caused by Gingivitis in Adults https://ClinicalTrials.gov/show/NCT00941668 Completed Colgate Palmolive 2008-08-31
NCT00932347 Effect of Mouthwash Containing Camellia Sinensis Extracts on Oral Malodor https://ClinicalTrials.gov/show/NCT00932347 Completed Mahidol University 2009-09-30
NCT00926328 Comparative Efficacy of a Toothpaste That Reduces Plaque and Gingivitis https://ClinicalTrials.gov/show/NCT00926328 Completed Colgate Palmolive 2007-12-31
NCT00885599 Efficacy of a Naturally-derived Mouthrinse for Gingival Inflammation https://ClinicalTrials.gov/show/NCT00885599 Completed Shaare Zedek Medical Center 2010-06-30
NCT00855933 A Controlled Clinical Study to Determine the Gingivitis Benefit of Flossing https://ClinicalTrials.gov/show/NCT00855933 Completed Procter and Gamble 2009-02-28
NCT03322124 Study to Assess the Inhibition of Plaque Formation in Subjects With a Gingival Index ≤1.5 https://ClinicalTrials.gov/show/NCT03322124 Completed Schülke & Mayr GmbH 2018-12-14
NCT02633345 Effects on Tablets Containing Probiotic Candidate Strains https://ClinicalTrials.gov/show/NCT02633345 Completed University of Copenhagen 2016-04-30
NCT02138552 Dose Finding Study to Assess Octenidine Mouthwash Concentrations in Comparison to Placebo https://ClinicalTrials.gov/show/NCT02138552 Completed Schülke & Mayr GmbH 2014-04-30
NCT04123002 Effect of Miswak Chewing Sticks on Periodontal Pathogens and Its Impact on the Progression of Gingivitis https://ClinicalTrials.gov/show/NCT04123002 Recruiting King Saud Bin Abdulaziz University for Health Sciences 2019-12-01
NCT02546804 A Clinical Trial to Study the Effects of Two Home Made Mouthwashes in Patients With Gum Diseases https://ClinicalTrials.gov/show/NCT02546804 Completed Government College of Dentistry, Indore 2015-10-31
NCT01637948 Controlled Clinical Trial of Traditional Chinese Medicine Mouthrinse https://ClinicalTrials.gov/show/NCT01637948 Completed The University of Hong Kong 2011-05-31
NCT03418246 Cervical Carious Lesions Restored With Calcium Silicate Based Cement (Biodentine) Compared With Glass-ionomer Cement https://ClinicalTrials.gov/show/NCT03418246 Completed Jordan University of Science and Technology 2015-06-30
NCT02883244 Curved Soft-Picks on Plaque Accumulation on Patients With Gingivitis https://ClinicalTrials.gov/show/NCT02883244 Completed Sunstar Americas 2017-05-31
NCT02102295 Effects of Antioxidant Dentifrice on Gingivitis https://ClinicalTrials.gov/show/NCT02102295 Completed Lion Corporation 2007-07-31
NCT03988374 Clinical Efficacy Evaluation of Three Dentifrices https://ClinicalTrials.gov/show/NCT03988374 Completed Church & Dwight Company, Inc. 2018-08-24
NCT03936569 A Clinical Study to Assess the Plaque and Gingivitis Effects of a Stannous Fluoride Dentifrice https://ClinicalTrials.gov/show/NCT03936569 Completed Procter and Gamble 2019-01-25
NCT00779909 Dose-dependent Anti-inflammatory Effects of Vitamin D in a Human Gingivitis Model https://ClinicalTrials.gov/show/NCT00779909 Completed Boston University 2011-05-31
NCT00762528 Compare Anti-inflammatory Dentifrices https://ClinicalTrials.gov/show/NCT00762528 Completed Colgate Palmolive 2010-02-28
NCT00762515 Clinical Study to Evaluate the Treatment of Gingivitis of Two Toothpastes https://ClinicalTrials.gov/show/NCT00762515 Completed Colgate Palmolive 2008-08-31
NCT00743548 Comparing the Inter-dental Brush to Dental Floss https://ClinicalTrials.gov/show/NCT00743548 Completed University of British Columbia 2010-11-30
NCT00681135 Mechanical Plaque Control and Gingivitis Reduction in Fixed Appliance Patients https://ClinicalTrials.gov/show/NCT00681135 Completed University of Jena 2010-12-31
NCT00391547 Pilot Efficacy Study to Treat Gingivitis https://ClinicalTrials.gov/show/NCT00391547 Completed Biomedical Development Corporation NA
NCT03620396 Comparison of Serum Trefoil Factor 3 in Patients With Gingivitis and Periodontitis After Scaling and Root Planing https://ClinicalTrials.gov/show/NCT03620396 Completed Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre 2017-01-17

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT04017507 The Effects of Oscillating-Rotating Electric Toothbrushes on Plaque and Gingival Health https://ClinicalTrials.gov/show/NCT04017507 Completed Procter and Gamble 2018-11-30
NCT03003858 Hyaluronic Acid and Gingivitis in Pediatrics https://ClinicalTrials.gov/show/NCT03003858 Completed Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico 2016-12-31
NCT02922010 A Follow-Up Survey of Oral Hygiene and Health Outcomes for Women Previously Enrolled in “OHMOM” https://ClinicalTrials.gov/show/NCT02922010 Completed Procter and Gamble 2017-06-30
NCT02885064 Shifts in the Oral Biofilm of Patients With Known Oral Health Risk Factors https://ClinicalTrials.gov/show/NCT02885064 Recruiting University of North Carolina, Chapel Hill 2021-09-30
NCT02808130 PERIODONTAL DISEASE AND HYPERLIPIDEMIA https://ClinicalTrials.gov/show/NCT02808130 Completed Ondokuz Mayıs University 2014-08-31
NCT02508987 Obesity and Oxidative Stress in Patients With Different Periodontal Status https://ClinicalTrials.gov/show/NCT02508987 Completed Ondokuz Mayıs University 2014-03-31
NCT04402996 Meteorin-like Levels in Individuals With Periodontitis https://ClinicalTrials.gov/show/NCT04402996 Recruiting Istanbul Saglik Bilimleri University 2020-07-03
NCT04299347 Influence of the Restorative Cervical Margin Placement on the Supracrestal Tissue Attachment https://ClinicalTrials.gov/show/NCT04299347 Completed University of Siena 2019-06-29
NCT04293718 Acquired Chronic Erosive Gingivitis: Clinical Relevance of Papillary Gingival Biopsy https://ClinicalTrials.gov/show/NCT04293718 Completed Assistance Publique - Hôpitaux de Paris 2019-07-31
NCT03970759 Meta-analysis of Stannous Fluoride and the Effects on Gingival Health https://ClinicalTrials.gov/show/NCT03970759 Completed Procter and Gamble 2018-11-30
NCT03928080 Diagnostic Accuracy of Rapid Non-clinical Screening Tests for Early Detection of Periodontitis https://ClinicalTrials.gov/show/NCT03928080 Recruiting The European Research Group on Periodontology (ERGOPerio) 2020-06-30
NCT03910205 Tumor Necrosis Factor-alpha and Interleukin-18 Levels in Children With Gingivitis and Type 1 Diabetes Mellitus https://ClinicalTrials.gov/show/NCT03910205 Completed Aydin Adnan Menderes University 2019-06-30
NCT01234948 Oral Malodour and Periodontal Disease-related Parameters https://ClinicalTrials.gov/show/NCT01234948 Completed Aristotle University Of Thessaloniki 2009-01-31
NCT03703245 Pooled Analysis of Clinical Data From Six GSK Studies to Investigate the Efficacy of a Dentifrice Containing 67% Weight by Weight (w/w) Sodium Bicarbonate on Gingivitis and Plaque Accumulation https://ClinicalTrials.gov/show/NCT03703245 Completed GlaxoSmithKline 2019-11-11
NCT00641901 A Study to Evaluate Associations Between Gingivitis and Pregnancy Outcomes https://ClinicalTrials.gov/show/NCT00641901 Completed University of Alabama at Birmingham 2009-07-31

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02178046 Non-Invasive Oral Biofilm Characterization https://ClinicalTrials.gov/show/NCT02178046 Recruiting University of California, Irvine 2020-06-30
NCT03264846 Endocan Levels at Polycystic Ovary Syndrome and Periodontal Inflammation https://ClinicalTrials.gov/show/NCT03264846 Completed Bezmialem Vakif University 2017-11-29